·  Identification of substance:

• Product details:
   
• Product name: Tri-n-octylphosphine oxide GR
   

·    2 Composition/Data on components:

• Chemical characterization:
             Description:                    (CAS#)                                        
  Tri-n-octylphosphine oxide                         (CAS# 78-50-2),               100%
   
• Identification number (s):
   
• EINECS Number: 403-470-9

·    3 Hazards identification

• Hazard description: Xi Irritant
   
• Information pertaining to particular dangers for man and environment
  R 36/37/38 Irritating to eyes, respiratory system and skin.
   
• Classification system
   
• HMIS ratings (scale 0-4)
  
    (Hazardous Materials Identification System)
  Health (acute effects) = 3
  Flammability = 1
  Reactivity = 1

·    4 First aid measures

• After inhalation
  Supply fresh air. If required, provide artificial respiration. Keep patient warm.
  Seek immediate medical advice.
   
• After skin contact
  Immediately wash with water and soap and rinse thoroughly.
  Seek immediate medical advice.
   
• After eye contact
  Rinse opened eye for several minutes under running water. Then consult a doctor.
   
• After swallowing Seek immediate medical advice.

·    5 Fire fighting measures

• Suitable extinguishing agents
  CO2, extinguishing powder or water spray. Fight larger fires with water spray.
   
• Special hazards caused by the material, its products of combustion or   resulting gases:
  In case of fire, the following can be released:
  Carbon monoxide (CO)
  Phosphorus oxides
  Hydrogen phosphide (Phosphine)
   
• Protective equipment:
  Wear self-contained respirator.
  Wear fully protective impervious suit.

·    6 Accidental release measures

• Person-related safety precautions:
  Wear protective equipment. Keep unprotected persons away.
  Ensure adequate ventilation
   
• Measures for environmental protection:
  Do not allow material to be released to the environment without proper governmental permits.
   
• Measures for cleaning/collecting: Ensure adequate ventilation.
   
• Additional information:
  See Section 7 for information on safe handling
  See Section 8 for information on personal protection equipment.
  See Section 13 for disposal information.

·    7 Handling and storage

• Handling
   
• Information for safe handling:
  Keep container tightly sealed.
  Store in cool, dry place in tightly closed containers.
  Ensure good ventilation at the workplace.
   
• Information about protection against explosions and fires:
  No special measures required.
   
• Storage
   
• Requirements to be met by storerooms and receptacles:
  No special requirements.
   
• Information about storage in one common storage facility:
  Store away from oxidizing agents.
   
• Further information about storage conditions:
  Keep container tightly sealed.
  Store in cool, dry conditions in well sealed containers.

·    8 Exposure controls and personal protection

• Additional information about design of technical systems:
  Properly operating chemical fume hood designed for hazardous chemicals and having an average face velocity of at least 100 feet per minute.
  
  Components with limit values that require monitoring at the workplace:
  Not required.
   
• Additional information: No data
   
• Personal protective equipment
   
• General protective and hygienic measures
  The usual precautionary measures for handling chemicals should be followed.
  Keep away from foodstuffs, beverages and feed.
  Remove all soiled and contaminated clothing immediately.
  Wash hands before breaks and at the end of work.
  Avoid contact with the eyes and skin.
   
• Breathing equipment: Use suitable respirator when high concentrations are present.
   
• Protection of hands: Impervious gloves
   
• Eye protection: Safety glasses
   
• Body protection: Protective work clothing.

·    9 Physical and chemical properties:

• General Information
   
• Form: Crystalline
   
• Color: White
   
• Odor: Sweet
   
•                                      Value/Range  Unit    Method      
   
• Change in condition
   
• Melting point/Melting range:                 47-52 ° C
   
• Boiling point/Boiling range:                   212 ° C     (@ 0.3mmHg)
   
• Sublimation temperature / start:                      Not determined
   
• Flash point:                                 > 110 ° C
   
• Ignition temperature:                               Not determined
   
• Decomposition temperature:         Not determined
   
• Danger of explosion: Product does not present an explosion hazard.
   
• Explosion limits:
   
• Lower:                             Not determined
   
• Upper:                             Not determined
   
• Vapor pressure:                    Not determined
   
• Density:               at   20 ° C            0.88 g/cm³
   
• Solubility in / Miscibility with
   
• Water:                             Slightly soluble
  Not determined

·   10 Stability and reactivity

• Thermal decomposition / conditions to be avoided: Decomposition will not occur if used and stored according to specifications.
   
• Materials to be avoided: Oxidizing agents
   
• Dangerous reactions No dangerous reactions known
   
• Dangerous products of decomposition:
  Carbon monoxide and carbon dioxide
  Phosphorus oxides (e.g. P2O5)
  Hydrogen phosphide (Phosphine)

·   11 Toxicological information

• Acute toxicity:
  LD/LC50 values that are relevant for classification:                   
  Oral: LD50: >10000 mg/kg (rat)
  Dermal: LD50: 2830 mg/kg (rbt)
   
• Primary irritant effect:
   
• on the skin: Irritant to skin and mucous membranes.
   
• on the eye: Irritating effect.
   
• Sensitization: No sensitizing effects known.
   
• Subacute to chronic toxicity: Inorganic phosphorus compounds may cause irritation and hemorrhages in the stomach as well as liver and kidney damage.  Bone structure may be attacked, especially the jaw and teeth.
   
• Additional toxicological information: To the best of our knowledge the acute and chronic toxicity of this substance is not fully known. No classification data on carcinogenic properties of this material is available from the EPA, IARC, NTP, OSHA or ACGIH.

·   12 Ecological information:

• General notes:
  Do not allow material to be released to the environment without proper governmental permits.

·   13 Disposal considerations

• Product:
   
• Recommendation
  Consult state, local or national regulations to ensure proper disposal.
   
• Uncleaned packagings:
   
• Recommendation: Disposal must be made according to official regulations.

·   14 Transport information

Not a hazardous material for transportation.

• DOT regulations:
   
• Hazard class:             None
   
• Land transport ADR/RID  (cross-border)
   
• ADR/RID class:                None
   
• Maritime transport IMDG:
   
• IMDG Class:               None
   
• Air transport ICAO-TI and IATA-DGR:
   
• ICAO/IATA Class:          None
   
• Transport/Additional information:  Not dangerous according to the above specifications.

·   15 Regulations

• Product related hazard informations:
   
• Hazard symbols: Xi Irritant
   
• Risk phrases:  36/37/38 Irritating to eyes, respiratory system and skin.
   
• Safety phrases: 26       In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
   
• National regulations All components of this product are listed in the U.S. Environmental Protection Agency Toxic Substances Control Act Chemical substance Inventory.
   
• Information about limitation of use: For use only by technically qualified individuals