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CAS
# 50-55-5 RESERPINE PURISS |
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Blulux Laboratories Pvt. Ltd |
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Section 1
- Product Identification
MSDS
Name: Reserpine Puriss
Synonyms:
Methylreserpate 3,4,5-Trimethoxybenzoic Acid; 3,4,5-Trimethoxybenzoyl
Methyl Reserpate.
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Section
2 - Composition, Information on Ingredients
CAS#
Chemical
Name
Percent EINECS/ELINCS
50-55-5
Reserpine
97 200-047-9
Hazard
Symbols: XN
Risk
Phrases: 20/21/22 44
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Section
3 - Hazards Identification
EMERGENCY
OVERVIEW
Appearance:
slightly yellow. Warning! Harmful if swallowed. May cause eye and skin
irritation.
May
cause respiratory and digestive tract irritation. May cause central nervous
system effects.
Target
Organs: Central nervous system.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
Harmful if swallowed. May cause gastrointestinal irritation with nausea,
vomiting and diarrhea. May cause central nervous system effects such as
psychosis, hallucinations, depression, visual changes and mental changes. May
cause nausea, vomiting, and drowsiness.
Inhalation:
May cause respiratory tract irritation.
Chronic:
May cause cancer according to animal studies. Adverse reproductive
effects have been reported in animals.
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Section
4 - First Aid Measures
Eyes:
Flush eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. If irritation develops, get medical aid.
Skin:
Flush skin with plenty of soap and water for at least 15 minutes while
removing contaminated clothing and shoes. Get medical aid if irritation
develops or persists. Wash clothing before reuse.
Ingestion:
Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse
mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing, give
artificial respiration. Get medical aid. Support breathing as needed. Do NOT
use mouth-to-mouth resuscitation.
Notes
to Physician: Treat symptomatically and supportively.
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Section
5 - Fire Fighting Measures
General
Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion.
Extinguishing
Media: Use agent most appropriate to extinguish fire. Use water
spray, dry chemical, carbon dioxide, or appropriate foam.
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Section
6 - Accidental Release Measures
General
Information: Use proper personal protective equipment as indicated in
Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the Protective
Equipment section. Avoid generating dusty conditions. Provide ventilation.
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Section
7 - Handling and Storage
Handling:
Wash thoroughly after handling. Use only in a well-ventilated area.
Minimize dust generation and accumulation. Avoid contact with skin and eyes. Do
not breathe dust, vapor, mist, or gas. Keep container tightly closed.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances. Poison room locked.
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Section
8 - Exposure Controls, Personal Protection
Engineering
Controls: Facilities storing or utilizing this material should be
equipped with an eyewash facility and a safety shower. Use adequate
general or local explosion-proof ventilation to keep airborne levels to
acceptable levels.
Exposure
Limits
Chemical
Name ACGIH NIOSH OSHA - Final PELs
Reserpine
none listed none listed none listed
OSHA
Vacated PELs: Reserpine: No OSHA Vacated PELs are listed for this
chemical.
Personal
Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical safety goggles as
described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or
European Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European
Standard EN 149. Always use a NIOSH or European Standard EN 149 approved
respirator when necessary.
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Section
9 - Physical and Chemical Properties
Physical
State: Crystalline powder
Appearance:
slightly yellow
Odor:
odorless
pH:
Not available.
Vapor
Pressure: Negligible
Vapor
Density: Not available.
Evaporation
Rate: Not available.
Viscosity:
Not available.
Boiling
Point: Decomposes
Freezing/Melting
Point: 264-265C
Auto
ignition Temperature: Not applicable.
Flash
Point: Not applicable.
Decomposition
Temperature:> 265 deg C
NFPA
Rating: (estimated) Health: 2; Flammability: 0; Reactivity: 0
Explosion
Limits, Lower: Not available.
Upper:
Not available.
Solubility:
Slightly soluble.
Specific
Gravity/Density: Not available.
Molecular
Formula:C33H40N2O9
Molecular
Weight:
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Section
10 - Stability and Reactivity
Chemical
Stability: Stable at room temperature in closed containers under normal
storage and handling conditions. Darkens and decomposes on exposure to light.
Conditions
to Avoid: Incompatible materials, light, dust generation, excess heat.
Incompatibilities
with Other Materials: Oxidizing agents.
Hazardous
Decomposition Products: Carbon monoxide, oxides of nitrogen, carbon dioxide.
Hazardous
Polymerization: Has not been reported
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Section
11 - Toxicological Information
CAS#
50-55-5
LD50/LC50:
CAS#
50-55-5:
Oral,
mouse: LD50 = >50 mg/kg;
Oral,
rat: LD50 = 420 mg/kg;
Carcinogenicity:
CAS#
50-55-5:
California:
carcinogen; initial date 10/1/89
NTP:
Suspect carcinogen
OSHA:
Possible Select carcinogen
IARC:
Group 3 carcinogen
Epidemiology:
Experimental tumorigenic data has been reported. Suspected carcinogen
with experimental carcinogenic, tumorig enic, and teratogenic data.
Teratogenicity:
Teratogenic effects have occurred in experimental animals.
Reproductive
Effects: Reproductive effects have occurred in experimental animals.
Neurotoxicity:
No information available.
Mutagenicity:
Mutagenic effects have occurred in experimental animals.
Other
Studies: See actual entry in RTECS for complete information.
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Section
12 - Ecological Information
Ecotoxicity:
No data available. No information available.
Environmental:
Terrestrial: Significant adsorption in soil can be predicted; however,
reserpine has a pKa of 6.6 which indicates that substantial ionization may
occur in moist soils. Aquatic: Absorbs UV light at environmental wavelengths
suggesting that direct photolysis may occur in water exposed to
sunlight.Atmospheric: Should exist almost entirely in the particulate phase in
the ambient atmosphere. Physical removal of particulate material may occur via
wet or dry deposition. Slight bioconcentration and biodegradation.
Physical:
No information available.
Other:
For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND
EXPOSURE DATA."
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Section
13 - Disposal Considerations
Chemical
waste generators must determine whether a discarded chemical is classified as a
hazardous waste. US EPA guidelines for the classification determination are
listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state
and local hazardous waste regulations to ensure complete and accurate
classification.
RCRA
P-Series: None listed.
RCRA
U-Series: CAS# 50-55-5: waste number U200.
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Section
14 - Transport Information
US
DOT IATA RID/ADR IMO Canada TDG
Shipping
Name: No information available.
Hazard
Class:
UN
Number:
Packing
Group:
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Section
15 - Regulatory Information
US
FEDERAL TSCA
CAS#
50-55-5 is listed on the TSCA inventory.
Health
& Safety Reporting List
None
of the chemicals are on the Health & Safety Reporting List.
Chemical
Test Rules
None
of the chemicals in this product are under a Chemical Test Rule.
Section
12b
CAS#
50-55-5: 5a2/12b/SARA 313
TSCA
Significant New Use Rule
CAS#
50-55-5 is a chemical with a Significant New Use Rule.
SARA
Section
302 (RQ)
CAS#
50-55-5: final RQ = 5000 pounds (2270 kg)
Section
302 (TPQ)
None
of the chemicals in this product have a TPQ.
Section
313
No
chemicals are reportable under Section 313.
Clean
Air Act:
This
material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2
Ozone depletors.
Clean
Water Act:
None
of the chemicals in this product are listed as Hazardous Substances under the
CWA. None of the chemicals in this product are listed as Priority Pollutants
under the CWA. None of the chemicals in this product are listed as Toxic
Pollutants under the CWA.
OSHA:
None
of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS#
50-55-5 can be found on the following state right to know lists: California,
New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts.
Hazard
Symbols:
XN
Risk
Phrases:
R
20/21/22 Harmful by inhalation, in contact with skin and if swallowed.
R
44 Risk of explosion if heated under confinement.
Safety
Phrases:
S
36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
S
45 In case of accident or if you feel unwell, seek medical advice immediately
(show the label where possible).
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Section 16 Preparation Information
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Prepared by: BLULUX LABORATORIES (P) LTD.
For questions contact: Blulux Laboratories
Pvt. Ltd.
79/66-B, I.H.I.Complex, Industrial Area, N.I.T. Faridabad,
Haryana-121001
TEL:
:++91-129-5021360, 2444433, 2237762
FAX:++ 91129-5027762 E-MAIL: blulux@rediffmail.com
The
statements contained herein are offered for informational purposes only and are
based upon technical data that Blulux Laboratories Pvt. Ltd. believes to be
accurate. It is intended for use only by persons having the necessary technical
skills and at their own discretion and risk. Since conditions and manner of use
are outside our control, we make NO WARRANTY, EXPRESS OR IMPLIED, OF
MERCHANTABILITY, FITNESS OR OTHERWISE.
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