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CAS
# 106-49-0 p-TOLUIDINE |
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Blulux Laboratories Pvt. Ltd |
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SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****
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Product
Name: p-Toluidine
Synonyms: 4-Aminotoluene; 4-Methylaniline; 4-Methylbenzenamine;
4-Toluidine;Tolylamine.
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**** SECTION 2 -
COMPOSITION, INFORMATION ON INGREDIENTS ****
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CAS# Chemical
Name
% EINECS#
---------------------------------------------------------------------------
106-49-0
p-Toluidine
100.0 203-403-1
Hazard Symbols: T N
Risk Phrases: 23/24/25
36 40 43 50
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**** SECTION 3 - HAZARDS IDENTIFICATION ****
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EMERGENCY OVERVIEW
Toxic by inhalation, in contact with skin and if swallowed.
Irritating to eyes. Possible risks of irreversible effects. May
cause sensitization by skin contact. Very toxic to aquatic
organisms.Light sensitive.
Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation. Harmful if absorbed through the skin. If
absorbed, causes symptoms similar to those of inhalation.
Ingestion: May cause irritation of the digestive tract. May be harmful if
swallowed. May form methemoglobin which in sufficient concentration
causes cyanosis (bluish discoloration of skin due to deficient
oxygenation of the blood).
Inhalation: May be fatal if inhaled. May cause drowsiness, unconsciousness,
and central nervous system depression. Inhalation causes anoxia due to
the formation of methemoglobin and hematuria. Inhalation may lead to dizziness,
weakness, and drowsiness, leading to stupor, unconsciousness, and even death.
Inhalation may produce headache and cyanosis of the lips, the mucous membranes,
and the fingernail beds, and the tongue. Exposure may affect the kidney and
bladder as evidenced by blood in the urine.
Chronic: Possible cancer hazard based on tests with laboratory animals. Chronic
inhalation may cause effects similar to those of acute
inhalation. Chronic
exposure leads to anemia, anorexia, weight loss, and cutaneous lesions.
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**** SECTION 4 - FIRST AID MEASURES ****
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Eyes:
In case of contact,
immediately flush eyes with plenty of water for
at least 15 minutes. Get
medical aid immediately.
Skin:
In case of contact,
immediately flush skin with plenty of water for
at least 15 minutes
while removing contaminated clothing and shoes.
Get medical aid
immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do not
induce vomiting unless directed to do so by
medical personnel. Never
give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
Poison material. If
inhaled, get medical aid immediately. Remove
victim to fresh air. If
not breathing, give artificial respiration.
If breathing is
difficult, give oxygen.
Notes to Physician:
If cyanosis is severe,
intravenous injection of Methylene blue,
1mg/kg of body weight
may be of value. For methemoglobinemia,
administer oxygen alone
or with Methylene blue depending on the
methemoglobinemia
concentration in the blood.
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**** SECTION 5 - FIRE FIGHTING MEASURES ****
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General Information:
As in any fire, wear a
self-contained breathing apparatus in
pressure-demand,
MSHA/NIOSH (approved or equivalent), and full
protective gear. Use
water spray to keep fire-exposed containers
cool. Combustible solid.
Extinguishing Media:
Use water spray, dry
chemical, carbon dioxide, or appropriate foam.
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**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
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General Information: Use proper personal protective
equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up
material and place into a suitable disposal
container. Avoid
generating dusty conditions. Remove all sources of
ignition. Approach spill
from upwind. Use water spray to cool and
disperse vapors and
protect personnel.
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**** SECTION 7 - HANDLING and STORAGE ****
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Handling:
Wash thoroughly after
handling. Remove contaminated clothing and
wash before reuse.
Minimize dust generation and accumulation. Do not
get in eyes, on skin, or
on clothing. Empty containers retain
product residue, (liquid
and/or vapor), and can be dangerous. Keep
container tightly
closed. Avoid contact with heat, sparks and flame.
Do not ingest or inhale.
Do not pressurize, cut, weld, braze,
solder, drill, grind, or
expose empty containers to heat, sparks or
open flames. Use only
with adequate ventilation.
Storage:
Keep away from heat,
sparks, and flame. Keep away from sources of
ignition. Store in a
tightly closed container. Store in a cool, dry,
well-ventilated area
away from incompatible substances. Poison room
locked. Store away from
heat, oxidizing agents, acids, alkalies, and
sunlight.
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**** SECTION 8 -
EXPOSURE CONTROLS, PERSONAL PROTECTION ****
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Engineering Controls:
Facilities storing or
utilizing this material should be equipped
with an eyewash facility
and a safety shower. Use adequate general or
local exhaust
ventilation to keep airborne concentrations below the
permissible exposure
limits.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR
1910.134 or European Standard EN 149. Always use a
NIOSH or European Standard EN 149 approved respirator
when necessary.
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****
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
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Physical State:
Solid
Appearance:
white to light brown
Odor:
aromatic odor
pH:
Not available.
Vapor
Pressure:
< 1 mm Hg @ 20 deg C
Viscosity:
Not available.
Boiling Point:
201 deg C
Freezing/Melting Point: 44 deg C
Auto ignition Temperature: 482 deg C ( 899.60 deg F)
Flash
Point:
88 deg C ( 190.40 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Insoluble.
Specific Gravity/Density: 1.05
Molecular Formula: C7H9N
Molecular Weight:
107.15
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**** SECTION 10 - STABILITY AND REACTIVITY ****
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Chemical Stability:
Stable under normal
temperatures and pressures. May discolor on
exposure to light.
Conditions to Avoid:
Ignition sources, dust
generation, excess heat, excess light.
Incompatibilities with Other Materials:
Oxidizing agents, acids,
bases, aromatic amines.
Hazardous Decomposition Products:
Nitrogen oxides, carbon
monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
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**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
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RTECS#:
CAS# 106-49-0: XU3150000
LD50/LC50:
CAS# 106-49-0: Draize
test, rabbit, eye: 100 mg Severe; Draize test,
rabbit, eye: 20 mg/24H
Moderate; Draize test, rabbit, skin: 500
mg/24H Severe; Draize
test, rabbit, skin: 500 mg/24H Mild;
Inhalation, rat: LC50 =
>640 mg/m3/1H; Oral, mouse: LD50 = 330
mg/kg; Oral, rabbit:
LD50 = 270 mg/kg; Oral, rat: LD50 = 336 mg/kg;
Skin, rabbit: LD50 = 890
mg/kg.
Carcinogenicity:
p-Toluidine -
ACGIH: A3 - Animal Carcinogen
NIOSH: occupational carcinogen
Other:
See actual entry in
RTECS for complete information.
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**** SECTION 12 - ECOLOGICAL INFORMATION ****
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**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
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Products which are considered hazardous for supply are classified as Special
Waste and the disposal of such chemicals is covered by regulations which may
vary according to location. Contact a specialist disposal company or the
local
waste regulator for advice. Empty containers must be decontaminated
before
returning for recycling.
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**** SECTION 14 - TRANSPORT INFORMATION ****
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IATA
Shipping Name:
TOLUIDINES
Hazard Class: 6.1
UN Number: 1708
Packing Group: II
IMO
Shipping Name:
TOLUIDINES
Hazard Class: 6.1
UN Number: 1708
Packing Group: II
RID/ADR
Shipping Name:
TOLUIDINES
Dangerous Goods Code: 6.1(12B)
UN Number: 1708
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**** SECTION 15 - REGULATORY INFORMATION ****
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European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 36 Irritating to eyes.
R 40 Possible risks of irreversible effects.
R 43 May cause sensitization by skin contact.
R 50 Very toxic to aquatic organisms.
Safety Phrases:
S 28A After contact with skin, wash immediately with
plenty of water.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/Safety data sheets.
WGK (Water Danger/Protection)
CAS# 106-49-0: 2
United Kingdom Occupational Exposure Limits
Canada
CAS# 106-49-0 is listed
on Canada's DSL List.
CAS# 106-49-0 is listed
on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 106-49-0:
OEL-AUSTRALIA:TWA 2 ppm (9 mg/m3);Skin;Carcinogen
OEL-BELGIUM:TWA 2 ppm
(8.8 mg/m3);Skin;Carcinogen
OEL-CZECHOSLOVAKIA:TWA 5
mg/m3;STEL 20 mg/m3 JAN9
OEL-DENMARK:TWA 2 ppm (9
mg/m3);Skin
OEL-THE NETHERLANDS:TWA 2
ppm (9 mg/m3);Skin JAN9
OEL-RUSSIA:STEL 1
mg/m3;Skin
OEL-SWITZERLAND:TWA 2
ppm (9 mg/m3);Skin
OEL IN BULGARIA,
COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND,
SINGAPORE, VIETNAM check ACGI TLV
US FEDERAL
TSCA
CAS# 106-49-0 is listed
on the TSCA inventory.
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**** SECTION 16 - ADDITIONAL INFORMATION ****
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Prepared by: BLULUX LABORATORIES (P) LTD.
For questions contact: Blulux Laboratories
Pvt. Ltd.
79/66-B, I.H.I.Complex, Industrial Area, N.I.T. Faridabad,
Haryana-121001
TEL:
:++91-129-5021360, 2444433, 2237762
FAX:++ 91129-5027762 E-MAIL: blulux@rediffmail.com
The
statements contained herein are offered for informational purposes only and are
based upon technical data that Blulux Laboratories Pvt. Ltd. believes to be
accurate. It is intended for use only by persons having the necessary technical
skills and at their own discretion and risk. Since conditions and manner of use
are outside our control, we make NO WARRANTY, EXPRESS OR IMPLIED, OF MERCHANTABILITY,
FITNESS OR OTHERWISE.
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