·  1 Identification of substance:

• Product details:
   
• Product name: L-Histidine monohydrochloride
   

·    2 Composition/Data on components:

• Chemical characterization:
    Description:                                    (CAS#)                                        
  L-Histidine monohydrochloride, monohydrate             (CAS# 7048-02-4):                               100%
   
• Identification number(s):
   
• EINECS Number: 211-438-9

·    3 Hazards identification

• Hazard description: · Not applicable
   
• Information pertaining to particular dangers for man and environment
  Not applicable
   
• Classification system
   
• HMIS ratings (scale 0-4)
  
    (Hazardous Materials Identification System)
  Health (acute effects) = 1
  Flammability = 1
  Reactivity = 1

·    4 First aid measures

• After inhalation
  Supply fresh air. If required, provide artificial respiration. Keep patient warm.
  Seek immediate medical advice.
   
• After skin contact
  Immediately wash with water and soap and rinse thoroughly.
  Seek immediate medical advice.
   
• After eye contact
  Rinse opened eye for several minutes under running water. Then consult a doctor.
   
• After swallowing Seek medical treatment.

·    5 Fire fighting measures

• Suitable extinguishing agents
  Carbon dioxide, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
   
• Special hazards caused by the material, its products of combustion or
    resulting gases:
  In case of fire, the following can be released:
  Carbon monoxide and carbon dioxide
  Nitrogen oxides (NOx)
  Hydrogen chloride (HCl)
   
• Protective equipment:
  Wear self-contained respirator.
  Wear fully protective impervious suit.

·    6 Accidental release measures

• Person-related safety precautions:
  Wear protective equipment. Keep unprotected persons away.
  Ensure adequate ventilation
   
• Measures for environmental protection:
  Do not allow material to be released to the environment without proper governmental permits.
   
• Measures for cleaning/collecting: Pick up mechanically.
   
• Additional information:
  See Section 7 for information on safe handling
  See Section 8 for information on personal protection equipment.
  See Section 13 for disposal information.

·    7 Handling and storage

• Handling
   
• Information for safe handling:
  Keep container tightly sealed.
  Store in cool, dry place in tightly closed containers.
  No special precautions are necessary if used correctly.
   
• Information about protection against explosions and fires:
  Keep ignition sources away.
   
• Storage
   
• Requirements to be met by storerooms and receptacles:
  No special requirements.
   
• Information about storage in one common storage facility:
  Store away from oxidizing agents.
   
• Further information about storage conditions:
  Keep container tightly sealed.
  Store in cool, dry conditions in well sealed containers.

·    8 Exposure controls and personal protection

• Additional information about design of technical systems:
  Properly operating chemical fume hood designed for hazardous chemicals and having an average face velocity of at least 100 feet per minute.
  
  Components with limit values that require monitoring at the workplace:
  Not required.
   
• Additional information: No data
   
• Personal protective equipment
   
• General protective and hygienic measures
  The usual precautionary measures for handling chemicals should be followed.
  Keep away from foodstuffs, beverages and feed.
  Remove all soiled and contaminated clothing immediately.
  Wash hands before breaks and at the end of work.
   
• Breathing equipment:
  Use suitable respirator when high concentrations are present.
   
• Protection of hands:
  Impervious gloves
  Check protective gloves prior to each use for their proper condition.
   
• Material of gloves
  The selection of suitable gloves not only depends on the material, but also on quality.  Quality will vary from manufacturer to manufacturer.
   
• Eye protection: Safety glasses
   
• Body protection: Protective work clothing.

·    9 Physical and chemical properties:

• General Information
   
• Form: Crystalline
   
• Color: White
   
• Odor: Not determined
   
•                                      Value/Range  Unit    Method      
   
• Change in condition
   
• Melting point/Melting range:               253-255 ° C     dec
   
• Boiling point/Boiling range:       Not determined
   
• Sublimation temperature / start:   Not determined
   
• Flash point:                       Not applicable
   
• Ignition temperature:              Not determined
   
• Decomposition temperature:         Not determined
   
• Danger of explosion: Product does not present an explosion hazard.
   
• Explosion limits:
   
• Lower:                             Not determined
   
• Upper:                             Not determined
   
• Vapor pressure:                    Not determined
   
• Density:                           Not determined
   
• Solubility in / Miscibility with Water:   Not determined

·   10 Stability and reactivity

• Thermal decomposition / conditions to be avoided:
  Decomposition will not occur if used and stored according to specifications.
   
• Materials to be avoided: Oxidizing agents
   
• Dangerous reactions No dangerous reactions known
   
• Dangerous products of decomposition:
  Carbon monoxide and carbon dioxide
  Nitrogen oxides
  Hydrogen chloride (HCl)

·   11 Toxicological information

• Acute toxicity:
   
• Primary irritant effect:
   
• on the skin: May cause irritation
   
• on the eye: May cause irritation
   
• Sensitization: No sensitizing effects known.
   
• Subacute to chronic toxicity:
  Other than potential irritation (see above), no information on illness or injury to humans from acute or chronic exposure to this product is available.
   
• Additional toxicological information:
  To the best of our knowledge the acute and chronic toxicity of this substance is not fully known.
  No classification data on carcinogenic properties of this material is available from the EPA, IARC, NTP, OSHA or ACGIH.

·   12 Ecological information:

• General notes:
  Do not allow material to be released to the environment without proper governmental permits.

·   13 Disposal considerations

• Product:
   
• Recommendation
  Consult state, local or national regulations to ensure proper disposal.
   
• Uncleaned packagings:
   
• Recommendation:
  Disposal must be made according to official regulations.

·   14 Transport information

Not a hazardous material for transportation.
 

• DOT regulations:
   
• Hazard class:             None
   
• Land transport ADR/RID  (cross-border)
   
• ADR/RID class:                None
   
• Maritime transport IMDG:
   
• IMDG Class:               None
  
   
• Air transport ICAO-TI and IATA-DGR:
   
• ICAO/IATA Class:          None
   
• Transport/Additional information:
  Not dangerous according to the above specifications.

·   15 Regulations

• Product related hazard information's:
  Observe the general safety regulations when handling chemicals
   
• National regulations
  All components of this product are listed in the U.S. Environmental Protection Agency Toxic Substances Control Act Chemical substance Inventory.
  All components of this product are listed on the Canadian Domestic Substances List (DSL).
   
• Information about limitation of use:
  For use only by technically qualified individuals.

·   16 Other information:

Prepared by: BLULUX LABORATORIES (P) LTD.

For questions contact: Blulux Laboratories Pvt. Ltd.

79/66-B, I.H.I.Complex, Industrial Area, N.I.T. Faridabad, Haryana-121001

TEL: :++91-129-5021360, 2444433, 2237762  FAX:++ 91129-5027762 E-MAIL: blulux@rediffmail.com

The statements contained herein are offered for informational purposes only and are based upon technical data that Blulux Laboratories Pvt. Ltd.  believes to be accurate. It is intended for use only by persons having the necessary technical skills and at their own discretion and risk. Since conditions and manner of use are outside our control, we make NO WARRANTY, EXPRESS OR IMPLIED, OF MERCHANTABILITY, FITNESS OR OTHERWISE.

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