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CAS
# 51 - 43 - 4 L - ADRENALINE |
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Blulux Laboratories Pvt. Ltd |
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Section 1 - Chemical Product and
Company Identification |
MSDS
Name: L - Adrenaline
Synonyms: l-3,4-Dihydroxy-Alpha-(Methylaminomethyl)Benzyl Alcohol;
Adrenaline, L(-)-Epinephrine
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Section 2 - Composition,
Information on Ingredients |
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CAS# |
Chemical
Name |
Percent |
EINECS/ELINCS |
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51-43-4 |
L - Adrenaline |
99 |
200-098-7 |
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Section 3 - Hazards
Identification |
EMERGENCY OVERVIEW
Appearance:
white to light beige crystalline powder.
Warning! Harmful if swallowed, inhaled, or absorbed through the skin. Causes
eye, skin, and respiratory tract irritation. May cause central nervous system
effects. May cause central nervous system depression. Light sensitive. Air
sensitive. May cause cardiac disturbances. The toxicological properties of this
material have not been fully investigated.
Target Organs: Central nervous system, respiratory system,
cardiovascular system, eyes, skin.
Potential Health Effects
Eye: Causes eye irritation. At high concentrations may cause
lacrimation (tearing) and irritation. May cause chemical conjunctivitis.
Skin: Causes skin irritation. May be absorbed through the skin
in harmful amounts.
Ingestion: May cause gastrointestinal irritation with nausea,
vomiting and diarrhea. May cause cardiac disturbances. The toxicological properties
of this substance have not been fully investigated. May cause central nervous
system depression. May be harmful if swallowed.
Inhalation: May cause respiratory tract irritation. The
toxicological properties of this substance have not been fully investigated.
May be harmful if inhaled. May cause cardiac damage. Can produce delayed
pulmonary edema. Inhalation at high concentrations may cause CNS depression and
asphixiation.
Chronic: Effects may be delayed.
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Section 4 - First Aid Measures |
Eyes: Immediately flush eyes with plenty of water for at least
15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion: Never give anything by mouth to an unconscious
person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse
mouth and drink 2-4 cupfuls of milk or water.
Inhalation: Remove from exposure and move to fresh air
immediately. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth
resuscitation.
Notes to Physician: Treat symptomatically and supportively.
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Section 5 - Fire Fighting
Measures |
General Information: As in any fire, wear a
self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or
equivalent), and full protective gear. During a fire, irritating and highly toxic
gases may be generated by thermal decomposition or combustion. Containers may
explode in the heat of a fire. Runoff from fire control or dilution water may
cause pollution.
Extinguishing Media: In case of fire, use water, dry chemical,
chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed
containers.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower: Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 0;
Instability: 1
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Section 6 - Accidental Release
Measures |
General Information: Use proper personal protective equipment
as indicated in Section 8.
Spills/Leaks: Clean up spills immediately, observing
precautions in the Protective Equipment section. Sweep up, then place into a
suitable container for disposal. Provide ventilation. Place under an inert
atmosphere.
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Section 7 - Handling and Storage
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Handling: Wash thoroughly after handling. Avoid contact with eyes,
skin, and clothing. Keep container tightly closed. Avoid ingestion and
inhalation. Store protected from light. Handle under an inert atmosphere. Store
protected from air. Wash clothing before reuse.
Storage: Keep refrigerated. (Store below 4°C/39°F.) Store in a
tightly closed container. Poison room locked/refrigerator. Do not expose to
air. Store protected from light. Store under an inert atmosphere.
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Section 8 - Exposure Controls,
Personal Protection |
Engineering Controls: Facilities storing or utilizing this
material should be equipped with an eyewash facility and a safety shower. Use
adequate general or local exhaust ventilation to keep airborne concentrations
below the permissible exposure limits.
Exposure Limits
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Chemical
Name |
ACGIH |
NIOSH |
OSHA -
Final PELs |
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L-Adrenaline |
none listed |
none
listed |
none
listed |
OSHA Vacated PELs: L(-)-Epinephrine: No OSHA Vacated PELs are
listed for this chemical.
Personal Protective Equipment
Eyes: Wear safety glasses and chemical goggles if splashing is
possible.
Skin: Wear appropriate protective gloves and clothing to
prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize
contact with skin.
Respirators: Wear a NIOSH/MSHA or European Standard EN 149 approved
full-facepiece airline respirator in the positive pressure mode with emergency
escape provisions.
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Section 9 - Physical and
Chemical Properties |
Physical State: Crystalline powder
Appearance: white to light beige
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:208-211 deg C
Decomposition Temperature:> 212 deg C
Solubility: slightly soluble
Specific Gravity/Density: Not available.
Molecular Formula:C9H13NO3
Molecular Weight:183.21
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Section 10 - Stability and
Reactivity |
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, light, exposure to air,
excess heat.
Incompatibilities with Other Materials: Acid chlorides, acids, oxidizing
agents.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide,
carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.
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Section 11 - Toxicological
Information |
RTECS#:
CAS# 51-43-4: DO2625000
LD50/LC50:
CAS# 51-43-4:
Skin, rat: LD50 = 62 mg/kg;<BR.
Carcinogenicity:
CAS# 51-43-4: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology: No information found.
Teratogenicity: No information found.
Reproductive Effects: Adverse reproductive effects have occurred in
experimental animals.
Mutagenicity: Mutagenic effects have occurred in experimental animals.
Neurotoxicity: No information found.
Other Studies:
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Section 12 - Ecological
Information |
Ecotoxicity: No data available. No information available.
Environmental: Terrestrial: No information found in the available
literature however, Epinephrine should be highly mobile in soils, and it may
leach to ground water. However, it is unstable in the presence of light, heat,
air and alkalies so it has the potential to undergo direct photolysis and
various chemical reactions in the soil. Aquatic Fate: None located in the
available literature however, expected to undergo changes similar to those
expected in soil. Atmospheric Fate: Expected to exist almost entirely in the
particulate phase in ambient air. It has an estimated half-life of about three
hours.
Physical: No information available.
Other: No information available.
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Section 13 - Disposal
Considerations |
Chemical waste generators must determine whether a discarded chemical is
classified as a hazardous waste. US EPA guidelines for the classification
determination are listed in 40 CFR Parts 261.3. Additionally, waste generators
must consult state and local hazardous waste regulations to ensure complete and
accurate classification.
RCRA P-Series: CAS# 51-43-4: waste number P042.
RCRA U-Series: None listed.
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Section 14 - Transport
Information |
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US DOT |
Canada
TDG |
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Shipping
Name: |
DOT regulated
- small quantity provisions apply (see 49CFR173.4) |
TOXIC
SOLID ORGANIC NOS (EPINEPHRINE) |
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Hazard
Class: |
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6.1 |
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UN
Number: |
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UN2811 |
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Packing
Group: |
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II |
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Section 15 - Regulatory
Information |
US FEDERAL
TSCA
CAS# 51-43-4 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health &
Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a
Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA
Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a
SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
CAS# 51-43-4: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 51-43-4: acute, chronic.
Section 313 No chemicals are reportable
under Section 313.
Clean Air Act:
This material does not contain any hazardous air
pollutants.
This material does not contain any Class 1 Ozone
depletors.
This material does not contain any Class 2 Ozone
depletors.
Clean Water Act:
None of the chemicals in this product are listed
as Hazardous Substances under the CWA.
None of the chemicals in this product are listed
as Priority Pollutants under the CWA.
None of the chemicals in this product are listed
as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are
considered highly hazardous by OSHA.
STATE
CAS# 51-43-4 can be found on the following state
right to know lists: New Jersey, Pennsylvania, Massachusetts.
California Prop 65
California No Significant Risk Level: None of the chemicals in this product are
listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
T
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with
skin and if
swallowed.
R 33 Danger of cumulative effects.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 23 Do not inhale gas/fumes/vapour/spray.
S 26 In case of contact with eyes, rinse
immediately with plenty of
water and seek medical advice.
S 36/37/39 Wear suitable protective clothing,
gloves and eye/face
protection.
S 45 In case of accident or if you feel unwell,
seek medical advice
immediately (show the label where possible).
WGK (Water Danger/Protection)
CAS# 51-43-4: 3
Canada - DSL/NDSL
CAS# 51-43-4 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D1A,
D2B.
Canadian Ingredient Disclosure List
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Section 16 - Additional
Information |
Prepared by: BLULUX LABORATORIES (P) LTD.
For questions contact:: Blulux Laboratories
Pvt. Ltd.
79/66-B, I.H.I.Complex, Industrial Area, N.I.T. Faridabad,
Haryana-121001
TEL:
:++91-129-5021360, 2444433, 2237762
FAX:++ 91129-5027762 E-MAIL: blulux@rediffmail.com
The
statements contained herein are offered for informational purposes only and are
based upon technical data that Blulux Laboratories Pvt. Ltd. believes to be
accurate. It is intended for use only by persons having the necessary technical
skills and at their own discretion and risk. Since conditions and manner of use
are outside our control, we make NO WARRANTY, EXPRESS OR IMPLIED, OF
MERCHANTABILITY, FITNESS OR OTHERWISE.
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