|
· Identification
of substance:
- Product
name: ISOPROPYLAMINE for Synthesis
|
|
· 2 Composition/Data
on components:
- Chemical
characterization:
Description:
(CAS#)
Isopropylamine
(CAS# 75-31-0); 100%
- EINECS
Number: 200-860-9
- EU
Number: 612-007-00-1
|
|
· 3 Hazards
identification
- Hazard
description:
Xi Irritant
F+ Extremely flammable
- Information
pertaining to particular dangers for man and environment
R 12 Extremely flammable.
R 36/37/38 Irritating to eyes, respiratory system and skin.
- Classification
system
- HMIS
ratings (scale 0-4)
(Hazardous Materials Identification System)
Health (acute effects) = 2
Flammability = 3
Reactivity = 1
|
|
· 4 First
aid measures
- General
information
Immediately remove any clothing soiled by the product.
In case of irregular breathing or respiratory arrest provide artificial
respiration.
- After
inhalation
Supply fresh air. If required, provide artificial respiration. Keep
patient warm.
Seek immediate medical advice.
- After
skin contact
Immediately wash with water and soap and rinse thoroughly.
Seek immediate medical advice.
- After
eye contact
Rinse opened eye for several minutes under running water. Then consult a
doctor.
- After
swallowing
Do not induce vomiting; immediately call for medical help.
Seek immediate medical advice.
|
|
· 5 Fire
fighting measures
- Suitable
extinguishing agents
In case of fire, use sand, carbon dioxide or powdered extinguishing
agent. Never use water.
- For
safety reasons unsuitable extinguishing agents
Water
- Special
hazards caused by the material, its products of combustion or
resulting gases:
In case of fire, the following can be released:
Carbon monoxide and carbon dioxide
Nitrogen oxides (NOx)
- Protective
equipment:
Wear self-contained respirator.
Wear fully protective impervious suit.
|
|
· 6 Accidental
release measures
- Person-related
safety precautions:
Wear protective equipment. Keep unprotected persons away.
Ensure adequate ventilation
Keep away from ignition sources
- Measures
for environmental protection:
Do not allow material to be released to the environment without proper
governmental permits.
- Measures
for cleaning/collecting:
Absorb with liquid-binding material (sand, diatomite, acid binders,
universal binders, sawdust).
Dispose contaminated material as waste according to item 13.
Ensure adequate ventilation.
Do not flush with water or aqueous cleansing agents
Keep away from ignition sources.
- Additional
information:
See Section 7 for information on safe handling
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.
|
|
· 7 Handling
and storage
- Handling
- Information
for safe handling:
Keep container tightly sealed.
Store in cool, dry place in tightly closed containers.
Keep away from heat and direct sunlight.
Ensure good ventilation at the workplace.
Open and handle container with care.
- Information
about protection against explosions and fires:
Keep ignition sources away.
Protect against electrostatic charges.
Fumes can combine with air to form an explosive mixture.
- Storage
- Requirements
to be met by storerooms and receptacles:
Store in a cool location.
- Information
about storage in one common storage facility:
Do not store together with oxidizing and acidic materials.
Store away from acid chlorides.
Store away from acid anhydrides.
- Further
information about storage conditions:
Keep container tightly sealed.
Store in cool, dry conditions in well sealed containers.
Protect from heat and direct sunlight.
Store under lock and key and with access restricted to technical experts
or their assistants only.
|
|
· 8 Exposure
controls and personal protection
- Additional
information about design of technical systems:
Properly operating chemical fume hood designed for hazardous chemicals
and having an average face velocity of at least 100 feet per minute.
- Components
with limit values that require monitoring at the workplace:
Isopropylamine
ppm
ACGIH TLV
5;
10-STEL
Belgium TWA
5; 10-STEL
Denmark TWA
5
France TWA
5
Germany TWA
5
Ireland TWA
5; 10-STEL
Netherlands TWA 5
Russia TWA
1
mg/m3
Switzerland TWA 5; 10-STEL
USA PEL
5
Components with limit values that require monitoring at the
workplace:
- Additional
information: No data
- Personal
protective equipment
- General
protective and hygienic measures
The usual precautionary measures for handling chemicals should be
followed.
Keep away from foodstuffs, beverages and feed.
Remove all soiled and contaminated clothing immediately.
Wash hands before breaks and at the end of work.
Store protective clothing separately.
Avoid contact with the eyes and skin.
- Breathing
equipment:
Use suitable respirator when high concentrations are present.
- Protection
of hands: Impervious gloves
- Eye
protection: Safety glasses
- Body
protection: Protective work clothing.
|
|
· 9 Physical
and chemical properties:
- General
Information
- Form:
Clear liquid
- Color:
Colorless
- Odor:
Amine-like /Ammonia-like
-
Value/Range Unit Method
- Change
in condition
- Melting
point/Melting range:
-101 ° C
- Boiling
point/Boiling range:
33-34 ° C
- Sublimation
temperature / start: Not determined
- Flash
point:
-37 ° C
- Ignition
temperature:
402 ° C
- Decomposition
temperature:
Not determined
- Auto
igniting:
Self igniting at raised temperature.
- Danger
of explosion: Product is not explosive. However, formation
of explosive air/vapor mixtures is possible.
- Explosion
limits:
- Lower:
2 Vol %
- Upper:
10.4 Vol %
- Vapor
pressure: at
20 ° C
0.237 hPa
- Density:
at
20 ° C
0.6891 g/cm³
- Bulk
density: at
20 ° C
683
kg/m³
- Solubility
in / Miscibility with
- Water:
Not miscible or difficult to mix
- Alcohols:
Soluble
- Organic
solvents:
Soluble in ether.
Soluble in acetone.
Soluble in benzene.
Soluble in chloroform.
- pH-value:
Alkaline
|
|
· 10 Stability
and reactivity
- Thermal
decomposition / conditions to be avoided:
Decomposition will not occur if used and stored according to
specifications.
- Materials
to be avoided:
Acids
Oxidizing agents
Acid chlorides
Acid anhydrides
1-Chloro-1,3-epoxypropane.
Perchloryl fluoride.
- Dangerous
reactions No dangerous reactions known
- Dangerous
products of decomposition:
Carbon monoxide and carbon dioxide
Nitrogen oxides
|
|
· 11 Toxicological
information
- Acute
toxicity:
LD/LC50 values that are relevant for classification:
Oral: LD50: 2700 mg/kg (gpg)
LD50: 2200 mg/kg (mus)
LD50: 111 mg/kg (rat)
LD50: 3200 mg/kg (rbt)
Dermal: LD50: 380 mg/kg (rbt)
Inhalative: LC50: 1800 mg/m3 (mam)
LC50/4H: 4000 ppm/4H (rat)
LCLo/30M: 7000 ppm/30M (mus)
Irritation of skin: moderate: 345 mg (rbt)
severe: 10 mg/24H (rbt)
Irritation of eyes: severe: 0.0689 ug (rbt)
- Primary
irritant effect:
- on
the skin: Irritant to skin and mucous membranes.
- on
the eye: Irritating effect.
- Sensitization: No
sensitizing effects known.
- Subacute
to chronic toxicity:
Isopropylamine is used as a solvent and used in rubber synthesis,
pharmaceuticals, dyes, insecticides, bactericides, textiles, and
surfactants. It is highly flammable, severely irritating to eyes and
mucous membranes, and toxic when ingested or through skin contact,
causing somnolence, dyspnea, hair loss, body temperature decrease and
gastro-intestinal disturbances. In high concentrations it is a narcotic
and has been known to cause sensitization in some cases.
- Additional
toxicological information:
Danger through skin absorption.
To the best of our knowledge the acute and chronic toxicity of this
substance is not fully known.
No classification data on carcinogenic properties of this material is
available from the EPA, IARC, NTP, OSHA or ACGIH.
|
|
· 12 Ecological
information:
- General
notes:
Do not allow material to be released to the environment without proper
governmental permits.
|
|
· 13 Disposal
considerations
- Product:
- Recommendation
Consult state, local or national regulations to ensure proper disposal.
- Un
cleaned packaging:
- Recommendation:
Disposal must be made according to official regulations.
|
|
· 14 Transport
information
- DOT
regulations:
- Hazard
class:
3
- Identification
number: UN1221
- Packing
group: I
- Proper
shipping name (technical name):
Isopropylamine
- Land
transport ADR/RID (cross-border)
- ADR/RID
class: 3
Flammable liquids
- Item:
22a
- Danger
code (Kemler): 338
- UN-Number:
1221
- Description
of goods: Isopropylamine
- Maritime
transport IMDG:
- IMDG
Class:
3
- UN
Number:
1221
- Packaging
group: I
- Proper
shipping name: Isopropylamine
- Air
transport ICAO-TI and IATA-DGR:
- ICAO/IATA
Class: 3
- UN/ID
Number:
1221
- Packaging
group: I
- Proper
shipping name: Isopropylamine
|
|
· 15 Regulations
- Product
related hazard information's:
- Hazard
symbols: Xi Irritant F+ Extremely flammable
- Risk
phrases:
12 Extremely flammable.
36/37/38 Irritating to eyes, respiratory system and skin.
- Safety
phrases:
16 Keep away from sources of
ignition - No smoking.
26 In case of contact with eyes,
rinse immediately with plenty of water and seek medical advice.
29 Do not empty into drains.
- National
regulations
All components of this product are listed in the U.S. Environmental
Protection Agency Toxic Substances Control Act Chemical substance
Inventory.
- Information
about limitation of use:
For use only by technically qualified individuals.
|
|
· 16 Other
information:
Prepared by: BLULUX LABORATORIES (P) LTD.
For questions contact: Blulux Laboratories
Pvt. Ltd.
79/66-B,
I.H.I.Complex, Industrial Area, N.I.T. Faridabad, Haryana-121001
The statements contained herein are offered for
informational purposes only and are based upon technical data that Blulux
Laboratories Pvt. Ltd. believes to be accurate. It is intended for use
only by persons having the necessary technical skills and at their own
discretion and risk. Since conditions and manner of use are outside our
control, we make NO WARRANTY, EXPRESS OR IMPLIED, OF MERCHANTABILITY, FITNESS
OR OTHERWISE.
|
