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CAS # 50 - 03 - 3 Hydrocortisone Acetate |
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Blulux Laboratories Pvt. Ltd |
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SECTION 1
- PRODUCT IDENTIFICATION AND HAZARDOUS COMPONENTS
PRODUCT:
Hydrocortisone Acetate
SYNONYMS:
Cortisol Acetate
MOLECULAR
FORMULA: C23H32O6
MOLECULAR
WEIGHT: 404.51
CHEMICAL
FAMILY: Steroid
INGREDIENT
(CAS #) % OSHA PEL ACGIH TLV
Hydrocortisone
Acetate (50-03-3) 100 N/A N/A
SECTION
2 - PHYSICAL AND CHEMICAL CHARACTERISTICS
BOILING
POINT: N/A VAPOR PRESSURE: N/A
MELTING
POINT: N/A VAPOR DENSITY: N/A
SPECIFIC
GRAVITY: N/A EVAPORATION RATE: N/A
(WATER
= 1) (BUTYL ACETATE = 1)
WATER
SOLUBILITY: 1 mg/100 ml WATER REACTIVE: No
APPEARANCE
AND ODOR: White to practically white powder. Odorless.
SECTION
3 - FIRE AND EXPLOSION DATA
FLASH
POINT (METHOD): N/A AUTO IGNITION TEMPERATURE: N/A
FLAMMABLE
LIMITS: LOWER: N/A UPPER: N/A
EXTINGUISHING
MEDIA: Water spray, carbon dioxide, dry chemical, foam.
SPECIAL
FIRE FIGHTING PROCEDURES: Fire fighters should wear full protective gear
including self-contained
breathing
apparatus.
UNUSUAL
FIRE AND EXPLOSION HAZARDS: May produce toxic fumes if heated to decomposition.
SECTION
4 - REACTIVITY HAZARD DATA
STABILITY:
Stable ( X ) Unstable ( )
INCOMPATIBILITY
(MATERIALS TO AVOID): None.
HAZARDOUS
DECOMPOSITION PRODUCTS: May produce toxic fumes if heated to decomposition.
HAZARDOUS
POLYMERIZATION: May Occur ( ) Will Not Occur ( X )
SECTION
5 - HEALTH HAZARD DATA
TOXICITY:
LD50: (intraperitoneal - rat) 2300 mg/kg
(subcutaneous
- mouse) 45.05 mg/kg
CARCINOGEN
LISTED BY: NTP Yes ( ) No ( X )
IARC
Yes ( ) No ( X )
OSHA
Yes ( ) No ( X )
Other
Yes ( ) No ( X )
ROUTES
OF ENTRY: Inhalation, ingestion, absorption, contact.
SIGNS
AND SYMPTOMS OF OVEREXPOSURE:
INHALATION:
May cause irritation of respiratory tract or allergic reaction.
EYE
CONTACT: May cause irritation or allergic reaction.
SKIN
CONTACT: May cause irritation or allergic reaction.
INGESTION:
May cause irritation of gastrointestinal tract or allergic reaction.
MSDS
- Hydrocortisone Acetate Page 2 of 4
CHRONIC
EFFECTS OF OVEREXPOSURE: Possible hyper sensitization.
MEDICAL
CONDITIONS AGGRAVATED BY OVEREXPOSURE: Hypersensitivity to this material.
Systemic
fungal
infection.
OTHER
PRECAUTIONS TO CONSIDER: Persons developing serious hypersensitivity
(anaphylactic) reactions must
receive
medical attention immediately. Exposure may cause suppression of adrenal gland
secretion, Cushing's
syndrome,
water retention, electrolyte imbalance, hyperglycemia.
EMERGENCY
FIRST AID PROCEDURES:
INHALATION:
Remove to fresh air. If not breathing, give artificial respiration. Seek
medical attention.
EYE
CONTACT: Flush with water for at least 15 minutes. If irritation persists or
develops, seek medical
attention.
SKIN
CONTACT: Wash with soap and water. If irritation persists or develops, seek
medical attention.
INGESTION:
Flush mouth with water and seek medical attention.
SECTION
6 - CONTROL AND PROTECTIVE MEASURES
RESPIRATORY
PROTECTION: NIOSH-approved respirator.
PROTECTIVE
GLOVES: Rubber.
EYE
PROTECTION: Safety glasses or goggles. Avoid wearing contact lenses when
working with this material due to
the
possibility of increased severity of eye damage.
VENTILATION:
Use local ventilation if airborne levels are high.
OTHER
PROTECTIVE EQUIPMENT: Appropriate laboratory apparel.
HYGIENIC
WORK PRACTICES: Do not eat, drink or smoke near this material. Wash any
contaminated clothing
before
reuse.
SECTION
7 - HANDLING AND STORAGE PRECAUTIONS
HANDLING
PRECAUTIONS: Avoid contact with skin, eyes or clothing. Avoid breathing dust.
STORAGE
PRECAUTIONS: Store in tight containers in a cool, dry place.
OTHER
PRECAUTIONS: Wash any exposed skin areas after handling. Wash any contaminated
clothing before
reuse.
SECTION
8 - SPILL AND DISPOSAL PROCEDURES
STEPS
TO BE TAKEN IN CASE OF SPILL OR DISCHARGE: Wear all protective clothing
including respirator,
gloves
and safety glasses/goggles. Vacuum or sweep up spillage and place in a tight
container. Wash spill area with
soap
and water. Wash any exposed skin area and wash contaminated clothing before
reuse.
WASTE
DISPOSAL METHOD: Dispose of in accordance with all applicable local, state,
federal, and environmental
regulations.
SECTION
9 - DISCLAIMER
The
statements contained herein are offered for informational purposes only and are
based upon technical data that Blulux Laboratories Pvt. Ltd. believes to
be accurate. It is intended for use only by persons having the necessary
technical skills and at their own discretion and risk. Since conditions and
manner of use are outside our control, we make NO WARRANTY, EXPRESS OR IMPLIED,
OF MERCHANTABILITY, FITNESS OR OTHERWISE _________________________________________________________________________________________
DEFINITIONS
OF ABBREVIATIONS USED:
ACGIH:
American Conference of Governmental Industrial Hygienists
CAS:
Chemical Abstract Service
IARC:
Internal Agency for Research on Cancer
IDLH:
Immediately Dangerous to Life or Health level
LC50:
Median Lethal Concentration
LD50:
Median Lethal Dose
N/A:
Not available
NTP:
National Toxicology Program
OSHA:
Occupational Safety and Health Administration
PEL:
Permissible Exposure Limit
STEL:
Short Term Exposure Limit
TLV:
Threshold Limit Value
________________________________________________________________________________________
Prepared by: BLULUX LABORATORIES (P) LTD.
For questions contact: Blulux Laboratories
Pvt. Ltd.
79/66-B, I.H.I.Complex, Industrial Area, N.I.T. Faridabad,
Haryana-121001
TEL:
:++91-129-5021360, 2444433, 2237762
FAX:++ 91129-5027762 E-MAIL: blulux@rediffmail.com
The statements contained herein
are offered for informational purposes only and are based upon technical data
that Blulux Laboratories Pvt. Ltd. believes to be accurate. It is intended for
use only by persons having the necessary technical skills and at their own
discretion and risk. Since conditions and manner of use are outside our
control, we make NO WARRANTY, EXPRESS OR IMPLIED, OF MERCHANTABILITY, FITNESS
OR OTHERWISE.
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