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CAS # 70-18-8 GLUTATHIONE, REDUCED for BIOCHEMISTRY |
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Blulux Laboratories Pvt. Ltd |
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HAZARD IDENTIFICATION
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Route Of Entry Inds - Inhalation: YES Skin: YES Ingestion: YES
Carcinogenicity Inds - NTP: NO IARC: NO OSHA: NO
Health Hazards Acute And Chronic: ACUTE: MAY BE HARMFUL BY INGESTION,
INHALATION OR ABSORPTION THROUGH SKIN. CHRONIC: THERE IS LIMITED EVIDENCE THAT
GLUTATHIONE, REDUCED, FREE ACID IS MUTAGENIC IN LABORATORY CELL CULTURES. UNTIL
FURTHER TESTING HAS BEEN DONE, IT SHOULD BE T REATED AS A POSSIBLE MUTAGEN IN
HUMANS.
Explanation of Carcinogenicity: N/P
Signs and Symptoms of Overexposure: SEE HEALTH HAZARDS.
Medical Conditions Aggravated by Overexposure: N/P
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FIRST AID
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IN CASE OF SKIN CONT, WASH W/COPIOUS AMTS OF WATER FOR AT LST 15 MINUTES.
REMOVE CONTAMD CLOTHING & SHOES AND WASH BEFORE WEARING. CONSULT PHYSICIAN.
IN CASES OF EYE CONT: FLUSH W/COPIOUS AMTS OF WATER FOR AT LST 15 MINUTES.
ASSURE ADEQUATE FLUSHING BY SEPARATING EYELIDS WITH FINGERS. CONSULT PHYSICIAN.
IN CASES OF INHALATION, REMOVE TO FRESH AIR & MONITOR BREATHING. IF BRTHG
BECOMES DFCLT, GIVE OXYG & CONSULT PHYSICIAN. IF BRTHG STOPS, GIVE ARTF
RESP & CONSULT PHYSICIAN. IN C ASES OF INGESTION, WASH MOUTH OUT W/WATER
& CONSULT LOCAL POISON CENTER & PHYSICIAN.
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FIRE FIGHTING MEASURES
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Flash Point Text: N/P
Auto Ignition Temperature Text:
Lower Limits: N/P Upper Limits: N/P
Extinguishing Media: DRY CHEMICL POWDER, CARBON DIOXIDE, WATER SPRAY, ALCOHOL
OR POLYMER FOAM.
Fire Fighting Procedures: WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS AND FULL PROTECTIVE CLOTHING TO PREVENT CONTACT WITH SKIN AND EYES.
Unusal Fire/Explosion Hazard: UPON THERMAL DECOMPOSITION, IT MAY EMIT TOXIC
GASES.
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RELEASE MEASURES
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Spill Release Procedures: EVACUATE AREA. WEAR NIOSH APPRVD RESPIRATOR, CHEMICAL
SAFETY GOGGLES, RUBBER BOOTS, & HEAVY RUBBER GLOVES. SWEEP UP & PLACE
IN SUITABLE CONTAINER. AVOID RAISING DUST. HOLD FOR APPROP DISPOSAL. WASH SPILL
& VENTILATE AREA AFTER MATERIAL PICK UP IS COMPLETE.
Neutralizing Agent: N/P
Waste Disposal Methods: COUNTRY, FEDERAL, STATE, AND LOCAL REGULATIONS ARE
VARIED AND CHANGE FREQUENTLY. FOR THIS REASON, WE RECOMMEND THAT YOU CONTACT
YOUR LOCAL DEPARTMENT OF HEALTH SERVICES FOR INFORMATION ON THE DISPOSAL OF
THIS PRODUCT OR ARRANGE FOR DISPOSAL BY A LICENSED DISPOSAL COMPANY.
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HANDLING AND STORAGE
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STORE IN A TIGHTLY CLOSED CONTAINER IN A +4C REFRIGERATOR. HYROSCOPIC. POSSIBLE
MUTAGEN. AVOID CONTACT WITH MATERIAL.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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Respiratory Protection: USE A NIOSH APPROVED RESPIRATOR.
Ventilation: HANDLE IN A CHEMICAL FUME HOOD WITH ADEQUATE VENTILATION.
Protective Gloves: CHEMICAL RESISTANT GLOVES.
Eye Protection: ANSI APPROVED CHEMICAL WORKERS GOGGLES (FP N).
Other Equipment: ANSI APPROVED EYE WASH & DELUGE SHOWER (FP N). WEAR
SUITABLE PROTECTIVE CLOTHING.
Work Hygenic Practices: ANSI APPROVED EYE WASH & DELUGE SHOWER (FP N). WEAR
SUITABLE PROTECTIVE CLOTHING.
Supplemental Safety & Health: SOL IN H*2O: SOLUBLE IN DMSO, ETHANOL, &
WATER. TOX INFO: LNG;HAM;DOSE: 1 MMOL/L CYTOGENETIC ANALYSIS 1985. CELL BIOLOGY
& TOX. 1(3), 123. OVR;HAM;DOSE: 1 MMOL/L CYTOGENETIC ANALYSIS 1978. CANCER
LETTERS. 5, 199. LNG;HAM;DOSE: 1 MMOL/L SIST ER CHROMATID EXCHANGE 1985. CELL
BIOLOGY & TOX. 193), 123. (OTHER INFO)
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PHYSICAL AND CHEMICAL PROPERTIES
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Boiling Point:
N/P
Melting/Freezing Point:
N/P
Decomposition Temp:
N/P
Vapor Pressure: N/P Vapor Density: N/P
Specific Gravity: N/P
PH: N/P
Viscosity: N/P
Evaporation Rate & Reference: N/P
Solubility in Water: SUPDAT
Appearance and Odor: WHITE SOLID. PACKAGED UNDER AN INERT GAS.
Percent Volatiles by Volume: N/P
Corrosion Rate: N/P
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STABILITY AND REACTIVITY
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Stability Indicator: YES
Stability Conditions to Avoid: STABLE UNDER NORMAL HANDLING PROCEDURES.
Materials to Avoid: NOT APPLICABLE.
Hazardous Decomposition Products: UPON THERMAL DECOMPOSITION, MAY EMIT TOXIC
GASES INCLUDING CARBON MONOXIDE, CARBON DIOXIDE, NITROGEN OXIDES AND SULFUR
OXIDES.
Hazardous Polymerization Products: NO
Conditions to Avoid Polymerization: N/P
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TOXICOLOGICAL
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RTECS NO: MC0556000. TOX DATA & REFERENCES: ORL; MUS; LD50: 5 G/KG 1972.
'MODERN PHARMACEUTICALS OF JAPAN, IV,' TOKYO JAPAN PHARMACEUTICAL, MEDICAL AND
DENTAL SUPPLY EXPORTERS' ASSOC. -, 93. IVN;MUS;LD50: 2238 MG/KG 1985. JANPANESE
JOURNAL OF ANTIBIOTICS. 38, 137. REPRO EFTS & REFERENCES: ORL;RAT;DOSE:
1250 MG/KG POST-IMPLANATION MORTALITY 1962. AMERICAN JOURNAL OF ANATOMY.
110,29. GENETIC DATA REFERENCES: FBR;HMN;DOSE: 1 MMOL/L UNSCHEDULE DNA
SYNTHESIS 1978. CANCER LETTERS . 5,199. LVR;RAT:DOSE: 1 MMOL/L DNA INHIBITION
1975. ARCHIVES OF BIOCHEMISTRY & PHYSICS. 166, 400. (SUPDAT)
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ECOLOGICAL
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NO INFORMATION FOUND.
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DISPOSAL
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COUNTRY, FEDERAL, STATE, AND LOCAL REGULATIONS ARE VARIED AND CHANGE
FREQUENTLY. FOR THIS REASON, WE RECOMMEND THAT YOU CONTACT YOUR LOCAL
DEPARTMENT OF HEALTH SERVICES FOR INFORMATION ON THE DISPOSAL OF THIS PRODUCT
OR ARRANGE FOR DISPOSAL BY A LICENSED DISPOSAL COMPANY.
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TRANSPORTATION
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UN NUMBER: N/A. PROPER SHIPPING NAME: N/A. IATA CLASS: N/A. IATA PACKING GROUP:
N/A.
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REGULATORY
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SARA Title III: AVOID CONTACT WITH MATERIAL. AVOID PROLONGED/REPEATED EXPOSURE.
WASH THROROUGHLY AFTER HANDLING. MATERIAL SHOULD ONLY BE HANDLED BY QUALIFIED,
EXPERIENCED PROFESSIONALS. THE ABOVE INFO IS BELIEVED TO BE CORRECT BUT DOES
NOT PURPORT TO BE A LL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE FOR
EXPERIENCED PERSONNEL. SUPDAT: OVR;HAM;DOSE: 100 UMOL/L SISTER CHROMATID
EXCHANGE 1979. MUTATION RESEARCH. 68,351. REFER TO REGISTY OF TOXIC EFTS OF
CHEM SUBSTANCES (RTECS) FOR DEFINITION OF ABBREVIATONS UDNED IN TOX TEXT &
FOR ADDNL INFO. RPT CNTNS ONLY SELECTED INFO FROM RTECS.
Federal Regulatory: Y
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OTHER
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