|
CAS # 58-85-5 D-(+)-BIOTIN for BIOCHEMISTRY |
|||
|
Blulux Laboratories Pvt. Ltd |
|
|
|
HAZARD
IDENTIFICATION
==============================================================================
Route Of Entry Inds - Inhalation: YES Skin: YES Ingestion: YES
Carcinogenicity Inds - NTP: NO IARC: NO OSHA: NO
Health Hazards Acute And Chronic: ACUTE EFFECTS: MAY BE HARMFUL BY INGESTION,
INHALATION OR ABSORPTION THROUGH SKIN. CHRONIC EFFECTS: THERE IS LIMITED
EVIDENCE THAT D-(+)-BIOTIN IS TERATOGENIC IN LABORATORY ANIMALS. UNTIL FURTHER
TESTING HAS BEEN DONE, IT SHOULD BE TREATED AS A POSSIBLE TERATOGEN IN HUMANS.
Explanation of Carcinogenicity: N/P
Signs and Symptoms of Overexposure: SEE HEALTH HAZARDS.
Medical Conditions Aggravated by Overexposure: N/P
==============================================================================
FIRST AID
==============================================================================
SKIN: WASH WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. REMOVE
CONTAMINATED CLOTHING AND SHOES AND WASH BEFORE WEARING. CONSULT MD. EYES:
FLUSH WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. ASSURE ADEQUATE
FLUSHING BY SEP ARATING EYELIDS WITH FINGERS. CONSULT MD. INHALATION: REMOVE TO
FRESH AIR AND MONITOR BREATHING. IF BREATHING BECOMES DIFFICULT, GIVE OXYGEN
AND CONSULT MD. IF BREATHING STOPS, GIVE ARTIFICIAL RESPIRATION AND CONSULT MD.
INGESTION: WASH MOU TH OUT WITH WATER AND CONSULT LOCAL POISON CENTER AND MD.
==============================================================================
FIRE FIGHTING MEASURES
==============================================================================
Flash Point Text: NOT APPLICABLE
Auto Ignition Temperature Text:
Extinguishing Media: DRY CHEMICAL POWDER, CARBON DIOXIDE, WATER SPRAY, ALCOHOL
OR POLYMER FOAM.
Fire Fighting Procedures: USE NIOSH APPROVED SCBA AND FULL PROTECTIVE EQUIPMENT
(FP N).
Unusal Fire/Explosion Hazard: UPON THERMAL DECOMPOSITION, IT MAY EMIT TOXIC
GASES.
==============================================================================
RELEASE MEASURES
==============================================================================
Spill Release Procedures: EVACUATE AREA. WEAR A NIOSH APPROVED RESPIRATOR,
CHEMICAL SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP AND
PLACE IN A SUITABLE CONTAINER. AVOID RAISING DUST. HOLD FOR APPROPRIATE
DISPOSAL. WASH SPILL SITE AND VENTILATE ARE A AFTER MATERIAL PICKUP IS
COMPLETE.
Neutralizing Agent: N/P
Waste Disposal Methods: COUNTRY, FEDERAL, STATE AND LOCAL REGULATIONS ARE
VARIED AND CHANGE FREQUENTLY. FOR THIS REASON, MFR RECOMMENDS THAT YOU CONTACT
YOUR LOCAL DEPARTMENT OF HEALTH SERVICES FOR INFORMATION ON THE DISPOSAL OF
THIS PRODUCT OR ARRANGE FOR DISPOSA L BY A LICENSED DISPOSAL COMPANY.
==============================================================================
HANDLING AND STORAGE
==============================================================================
STORE IN A TIGHTLY CLOSED CONTAINER IN A COOL, DRY PLACE (+20C). POSSIBLE
TERATOGEN. AVOID CONTACT WITH MATERIAL. AVOID PROLONGED OR REPEATED EXPOSURE.
POSSIBLE RISK OF IRREVERSIBLE EFFECTS. DO NOT BREATHE DUST. AVOID CONTACT WITH
SKIN AND EYES.
==============================================================================
EXPOSURE CONTROLS/PERSONAL PROTECTION
==============================================================================
Respiratory Protection: USE A NIOSH APPROVED RESPIRATOR.
Ventilation: HANDLE IN A CHEMICAL FUME HOOD WITH ADEQUATE VENTILATION.
Protective Gloves: CHEMICAL RESISTANT GLOVES.
Eye Protection: ANSI APPROVED CHEMICAL WORKERS GOGGLES & FULL LENGTH
FACESHIELD (FP N).
Other Equipment: ANSI APPROVED EYE WASH & DELUGE SHOWER (FP N). WEAR
SUITABLE PROTECTIVE CLOTHING.
Work Hygenic Practices: ANSI APPROVED EYE WASH & DELUGE SHOWER (FP N). WEAR
SUITABLE PROTECTIVE CLOTHING.
Supplemental Safety & Health: MFR'S INFO: MFR'S FAX #: (619) 452-3552;
MFR'S INFO ON INGS: MOLECULAR WEIGHT: 244.3. MOLECULAR FORMULA:
C*10H*16N*2O*3S. -- PHYSICAL & CHEMICAL PROPERTIES: SOLUBILITY: SOLUBLE IN
CHLOROFORM.
==============================================================================
PHYSICAL AND CHEMICAL PROPERTIES
==============================================================================
Boiling Point:
N/P
Melting/Freezing Point: >232.C, 449.6F
232-233C
Decomposition Temp:
N/P
Vapor Pressure: N/P Vapor Density: N/P
Specific Gravity: N/P
PH: N/P
Viscosity: N/P
Evaporation Rate & Reference: N/P
Solubility in Water: SEE SUPP DATA
Appearance and Odor: SOLID.
Percent Volatiles by Volume: N/P
Corrosion Rate: N/P
==============================================================================
STABILITY AND REACTIVITY
==============================================================================
Stability Indicator: YES
Stability Conditions to Avoid: STABLE UNDER NORMAL HANDLING PROCEDURES.
Materials to Avoid: NOT APPLICABLE.
Hazardous Decomposition Products: UPON THERMAL DECOMPOSITION, MAY EMIT TOXIC
GASES INCLUDING CARBON MONOXIDE, CARBON DIOXIDE, NITROGEN OXIDES AND SULFUR
OXIDES.
Hazardous Polymerization Products: N/P
Conditions to Avoid Polymerization: N/P
==============================================================================
TOXICOLOGICAL
==============================================================================
REPRO EFFECTS & REFERENCES: ORL; MUS; DOSE: 17 MG/KG TOXIC MATERNAL EFTS
1996. "EXPERIENTIA". 52, 149. SCU; RAT; DOSE: 200 MG/KG
POST-IMPLANTATION MORTALITY 1975. "JOURNAL OF NUTRITIONAL SCIENCE AND
VITAMINOLOGY". 21, 89. SCR; RAT; DOSE: 1 00 MG/KG EXTRA EMBRYONIC
STRUCTURES; FETOTOXICITY 1973. "CURRENT SCIENCE". 42, 613. SCU; RAT;
DOSE: 200 MG/KG EXTRA EMBRYONIC STRUCTURES; FETOXICITY 1976. "JOURNAL OF
NUTRITIONAL SCIENCE AND VITAMINOLOGY". 22, 181. REFER TO RTECS FOR A DEF
INITION OF ABBREVIATIONS USED IN TEXT AND FOR ADDITIONAL INFORMATION. THIS
REPORT CONTAINS ONLY SELECTED INFORMATION FROM RTECS.
==============================================================================
ECOLOGICAL
==============================================================================
NO INFORMATION AVAILABLE.
==============================================================================
DISPOSAL
==============================================================================
COUNTRY, FEDERAL, STATE AND LOCAL REGULATIONS ARE VARIED AND CHANGE FREQUENTLY.
FOR THIS REASON, MFR RECOMMENDS THAT YOU CONTACT YOUR LOCAL DEPARTMENT OF
HEALTH SERVICES FOR INFORMATION ON THE DISPOSAL OF THIS PRODUCT OR ARRANGE FOR
DISPOSA L BY A LICENSED DISPOSAL COMPANY.
==============================================================================
TRANSPORTATION
==============================================================================
UN NUMBER: N/A. PROPER SHIPPING NAME: N/A. IATA CLASS: N/A. IATA PACKING GROUP:
N/A.
==============================================================================
REGULATORY
==============================================================================
SARA Title III: AVOID CONTACT WITH MATERIAL. AVOID PROLONGED OR REPEATED
EXPOSURE. WASH THOROUGHLY AFTER HANDLING. MATERIAL SHOULD ONLY BE HANDLED BY
QUALIFIED, EXPERIENCED PROFESSIONALS. THE ABOVE INFORMATION IS BELIEVED TO BE
CORRECT BUT DOES NOT PURPOR T TO BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A
GUIDE FOR EXPERIENCED PERSONNEL.
Federal Regulatory: Y
==============================================================================
OTHER
==============================================================================
|
|
|
Mfgs. & Exporters: Laboratory Reagents, Fine Chemicals,
Analytical Reagents & Dehydrated Culture Media |
|
|
|
|
